IL-3 Protéine
Aperçu rapide pour IL-3 Protéine (ABIN935490)
Antigène
Voir toutes IL-3 ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
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Attributs du produit
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Purified recombinant Human IL3 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
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Buffer
- Supplied lyophilized with no additives.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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- IL-3 (Interleukin 3 (IL-3))
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Autre désignation
- IL3
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Sujet
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IL3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL3 may have additional immunoregulatory roles. Many of the IL3 activities depend upon co-stimulation with other cytokines.
Alternative Names: IL-3 protein, Multi-CSF protein, Interleukin 3 protein, HCGF protein, IL-3, IL 3, IL-3 protein, IL 3 protein, Mast cell growth factor protein, MCGF protein, P-cell stimulation factor protein, IL3 -
Poids moléculaire
- 15 kDa
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Pathways
- Signalistation JAK/STAT, Regulation of Carbohydrate Metabolic Process, Autophagy
Antigène
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